Based on recent studies, MAS is now a main treatment even for the moderate to severe forms of obstructive sleep apnoea (OSA).
A recent study(1) demonstrates that health outcomes in patients with moderate to severe obstructive sleep OSA were similar after treatment with continuous positive airway pressure (CPAP) and MAS. This was likely explained by the greater efficacy of CPAP being offset by the greater compliance with MAS.
In another study(2) by Cistiulli and Sutherland it was demonstrated that 77% of patients still consistently used their oral appliance at one year. In comparison, only 46% of CPAP users maintain at least 4 hours of therapy on more than 70% of nights.
When you take into account that around 50% of people diagnosed with OSA decline to even have a CPAP trial, MAS becomes an important treatment even for the people with moderate to severe disease.
However not all therapy with MAS is the same and optimal results are predicated on using new generation well fitting, optimally titrated appliances.
(1) Health Outcomes of CPAP versus Oral Appliance Treatment for Obstructive Sleep Apnea: A Randomised Controlled Trial
American Journal of Respiratory and Critical Care Medicine February, 2013
Craig L Phillips, Ronald R Grunstein, M. Ali Darendeliler
Anastasia S Mihailidou, Vasantha K Srinivasan, Brendon J Yee, Guy B Marks, and Peter A Cistulli
(2) Mandibular advancement splints for the treatment of sleep apnoea syndrome
Journal of Medical Sciences 2011
Kate Sutherland, Peter A. Cistulli